6 major harms to the body caused by obesity in men

　　 1. Diabetes

　　Obesity and diabetes are closely related. A survey of more than 310,000 people in 14 provinces and cities in my country showed that the incidence rate of diabetes in the normal population is 0.26%, while the incidence rate in overweight people is 2.82%, which is more than 10 times the former. Obese people eat more than the body needs. Excessive eating stimulates the pancreatic islets to secrete excess insulin, leading to hyperinsulinemia. Since the cells of obese people are insensitive to insulin, insulin secretion will be further promoted, which will increase the load on the pancreatic islets and lead to the proliferation and hypertrophy of the islet cells. In the long term, it can lead to pancreatic islet failure and diabetes. In addition, obesity is often accompanied by Hyperlipidemia Disease, hyperlipidemia often occurs, which increases free fatty acids, aggravates glucose metabolism disorders, and is more likely to induce diabetes.

　　2. High blood pressure

　　Obesity is a risk factor for the development of hypertension. A survey of middle-aged and elderly people showed that the prevalence of hypertension was 7.55% for those with a body mass index less than 20, 20.26% for those with a body mass index between 24 and 26, and 36.89% for those with a body mass index greater than 28. Obese people have a large increase in fat tissue, which requires increased blood volume and cardiac output to meet the body's needs. Long-term cardiac overload causes left ventricular hypertrophy and elevated blood pressure. Secondly, obese people often have hyperinsulinemia. Insulin can promote the reabsorption of sodium by the renal distal tubules, causing sodium retention and causing hypertension. In addition, the adrenal cortex function of obese people is active, the cortisol conversion rate is increased, and the hydroxylation of corticosterone and deoxycorticosterone is enhanced, which can increase blood pressure. Therefore, obesity is an important risk factor for hypertension.

　　3. Arteriosclerosis and coronary heart disease

　　According to survey data, the prevalence of coronary heart disease for those with a body mass index less than 20 is 4.72%, for those with a body mass index of 24-26, the prevalence of coronary heart disease is 9.91%, and for those with a body mass index greater than 28, the prevalence is as high as 16.51%. Obese people often have hypertriglyceridemia, which can cause atherosclerosis. Factors such as overweight, increased body surface area, excess adipose tissue, and increased cardiac load (including increased myocardial load caused by fat deposition inside and outside the myocardium) can cause cardiac ischemia and hypoxia. Obese people reduce physical activity, and coronary collateral circulation is weakened or insufficient. All the above factors can lead to arteriosclerosis and coronary heart disease.

　　4. Respiratory insufficiency

　　clinical It is called obesity-hypoventilation syndrome, also known as hypoventilation syndrome.

　　Extremely obese people have excessive fat on their chest and abdominal walls, which restricts their respiratory activities and causes shallow breathing. The expiratory supplementary volume is reduced, resulting in a reduction in functional residual volume, which puts the lungs in a position close to expiration. Due to the reduced tidal volume, alveolar ventilation is reduced, ventilation is restricted, resulting in carbon dioxide retention, arterial blood oxygen saturation decreases, and the patient may develop cyanosis. Due to long-term hypoxia, polycythemia can occur secondary to increased blood viscosity, increased circulatory resistance, increased cardiac load, pulmonary hypertension, and chronic pulmonary heart disease.

　　5.fatty liver

　　Obesity can cause fatty degeneration of the liver, leading to liver enlargement. In obese patients, due to long-term high-carbohydrate, high-fat diet and the presence of hyperinsulinemia, the rate of liver synthesis of triglycerides greatly exceeds the ability to transport triglycerides out of the liver, or it may cause obstacles in the transport of triglycerides by very low-density lipoprotein, leading to the accumulation of triglycerides in the liver and the occurrence of fatty liver.

　　6. Biliary tract disease

　　The incidence of cholecystitis and cholelithiasis in obese patients increases with the degree of obesity and age, and is related to the increased synthesis of endogenous cholesterol in the liver and other tissues of obese patients. The ratio of bile salts plus lecithin to cholesterol in normal bile is 11:1. If the cholesterol ratio increases, cholesterol will precipitate, crystallize and precipitate, easily melting and forming gallstones. Gallstones have a direct irritating effect on the gallbladder mucosa and can easily cause secondary bacterial infection and the formation of cholecystitis.

　　Editor’s tip: The above introduces the six major harms of obesity to the body, so everyone should pay attention to their health, pay attention to moderation in diet, and participate in more exercise , be more active and reduce the occurrence of obesity.