What happens if the endometrium is thick and prevents menstruation?

Thick endometrium and the absence of menstruation may be related to factors such as endocrine disorders, polycystic ovary syndrome, endometrial lesions, excessive mental stress, and the influence of drugs. Interventions can be made by adjusting lifestyle, drug treatment, surgical treatment, etc.

1. Endocrine disorders

Staying up late for a long time or excessive dieting may lead to hypothalamic-pituitary-ovarian axis dysfunction, abnormal estrogen secretion, thickening of the endometrium but no ovulatory menstruation. It is accompanied by symptoms such as breast tenderness and mood swings. You can use progesterone capsules, dydrogesterone tablets and other drugs to adjust the cycle as directed by your doctor, along with regular work and rest and a balanced diet.

2. Polycystic ovary syndrome

Excessive androgens inhibit follicular development, leading to continued anovulatory endometrium hyperplasia. Symptoms such as increased body hair and acne are common. Ethinyl estradiol and cyproterone tablets need to be used under the guidance of a doctor to regulate hormones, and metformin tablets can be used to improve insulin resistance.

3. Endometrial lesions

Endometrial polyps or atypical hyperplasia may prevent the lining from shedding normally. Ultrasound examination shows abnormal echogenic masses. Mild lesions can be controlled with levonorgestrel sustained-release intrauterine system, while severe lesions require hysteroscopic endometrial resection.

4. Excessive mental pressure

Chronic anxiety inhibits gonadotropin-releasing hormone secretion, leading to anovulatory amenorrhea. Physical symptoms such as headache and insomnia may occur. It is recommended to relieve stress through mindfulness training, and if necessary, take short-term oryzanol tablets to regulate autonomic nerve function.

5. Effects of drugs

Long-term use of emergency contraceptive pills or corticosteroids may interfere with cyclic changes in the endometrium. Most of the symptoms will recover on their own after stopping the drug, but those with persistent amenorrhea need to use estradiol valerate tablets to reestablish the menstrual cycle.

It is necessary to maintain moderate daily exercise such as yoga or brisk walking to avoid high-fat diet aggravating endocrine disorders. It is recommended to record the basal body temperature and monitor ovulation. If amenorrhea lasts for more than 3 months or is accompanied by severe abdominal pain, a gynecological consultation is required in time. A personalized treatment plan can be formulated after excluding organic diseases. Regular gynecological ultrasound examinations can help assess the status of the endometrium.